Subretinal fluid and vitreous proteomics in rhegmatogenous retinal detachment

Subretinal fluid and vitreous proteomics in rhegmatogenous retinal detachment - SRF Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00036632

Enrollment

Registered

2025-06-23

Start date

2026-02-01

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H33.0

Interventions

Group 1: pseudophakic retinal detachment: During vitrectomy the vitreous and the subretinal fluid will be sampled and afterwards stored at -80° C. Postoperatively clinical findings were documented on

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Cataract surgery done, retinal detachment, macular hole, gliosis

Exclusion criteria

Exclusion criteria: uveitis, glaucoma, diabetic retinopathy, intraocular tumor, active wet macular degeneration, retinal vein occlusion, systemic diseaes, PVR grade C or D

Design outcomes

Primary

Measure	Time frame
Occurence of retinal re-detachments after primary successful surgery in relation to the protein composition of the subretinal fluid and the vitreous. The postoperative course will be documented by clinical examinations (funduscopy) at day 1, week 4, and month 6 after surgery.	—

Secondary

Measure	Time frame
Differences between subretinal and vitreal proteome	—

Countries

Germany

Contacts

Public ContactPeter Walter

Klinik für Augenheilkunde, Uniklinik RWTH Aachen

pwalter@ukaachen.de+492418088191

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026