Validation of an artificial intelligence-driven 3D vectorcardiography for noninvasive detection of heart failure with preserved left ventricular function (HFpEF)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00036596

Enrollment

Registered

2025-04-28

Start date

2025-04-29

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure with preserved left ventricular function (HFpEF) I50

Interventions

Group 1: Group with HFpEF: 45 patients with heart failure with preserved left ventricular function (HFpEF) who fulfil the inclusion and exclusion criteria and have given written informed consent will

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: The following inclusion criteria apply to identify suitable patients for the HFpEF group: - Written informed consent available - Chronic, symptomatic heart failure (NYHA II-IV) with preserved systolic LV function (HFA-PEFF score =5 points) in the stage of clinical recompensation The following inclusion criteria apply to identify suitable patients for the control group: - Written informed consent available - Exclusion of chronic, symptomatic heart failure (NYHA II-IV) with preserved LV systolic function (HFA-PEFF score =5 points) in the stage of clinical recompensation

Exclusion criteria

Exclusion criteria: The following exclusion criteria apply to both the group with HFpEF and the control group: - lack of written patient consent - lack of patient capacity to consent - simultaneous participation in other intervention studies - pregnancy - an existing employment relationship or other dependent relationship with the applicant Clinic for Internal Medicine III

Design outcomes

Primary

Measure	Time frame
The primary aim of the study is to validate the S-factor in terms of sensitivity, specificity and the positive and negative predictive values for the diagnosis of heart failure with preserved pumping function (HFpEF) in comparison to echocardiography.	—

Secondary

Measure	Time frame
Secondarily, the diagnostic quality of other AI-supported vectorcardiography parameters will be assessed in comparison with echocardiography. Of particular interest is whether AI- supported vectorcardiography in combination with the risk predictors (gender, arterial hypertension, diabetes, coronary heart disease) offers a comparable diagnostic value compared to echocardiography.	—

Countries

Germany

Contacts

Public ContactArash Arya

Universitätsklinik und Poliklinik für Innere Medizin III

arash.arya@uk-halle.de+49 345 557-4910

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026