K51.9 K50.9
Conditions
Interventions
Group 1: As part of the study, targeted ultrasound examinations of the inflamed bowel segments are conducted, along with a clinical assessment of the current inflammatory activity.
The primary examin
Sponsors
Universitätsklinikum Halle (Saale), Anstalt öffentlichen Rechts und Martin-Luther-Universität Halle-Wittenberg, Medizinische Fakultät
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Chronic inflammatory bowel disease with clinical suspicion of an acute flare-up - Bowel wall thickness in the affected section > 3 mm - Written informed consent
Exclusion criteria
Exclusion criteria: - Infectious enteritis - Pregnancy / breastfeeding - Non-essential medication therapy for the acute flare-up - Non-consenting patients - Inadequate examination conditions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The intestinal vascularization as a predictor for activity of inflammation shows a significant reduction after start of therapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. After start of therapy a decrease of intestinal stiffness measured by strain and shear wave elastography is measured 2. Thickness of the intestinal wall decreases after a positive response to therapy. 3. Sonographic methods correlate well with clinical, laboratory and endoscopic markers of activity | — |
Countries
Germany
Contacts
Public ContactValentin Blank
Universitätsklinikum Halle (Saale)
Outcome results
None listed