C50 Z80
Conditions
Interventions
Group 1: Women carrying a BRCA1 or BRCA2 pathogenic variant who opted for risk-reducing mastectomy (RRM group), the intensified breast cancer surveillance (IBS group) or neither of the two measures at
Sponsors
Zentrum Familiärer Brust- und Eierstockkrebs, Universitätsklinikum Köln
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: • Women with pathogenic variants in the BRCA1 or BRCA2 genes who were recruited in MoreRisk and SYSKON • Women with unilateral breast cancer and women without breast cancer • Consent to being contacted again by the HerediCaRe register • Informed consent for study participation • Sufficient language skills in German
Exclusion criteria
Exclusion criteria: • Women with palliative care in cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Which specific prevention measures did the women opt for over the time? 2. How significant are the psychosocial and clinical factors for the decision? 3. How did the psychosocial factors develop over time and in relation to the selected prevention measures? | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality improvement of the structured and evidence-based preventive healthcare service for women with an increased risk of breast and ovarian cancer | — |
Countries
Germany
Contacts
Public ContactKerstin Rhiem
Zentrum Familiärer Brust- und Eierstockkrebs Universitätsklinikum Köln
Outcome results
None listed