Structure-Function Correlation in Diabetic Retinal Disease using Innovative High-Resolution Imaging and Lesion-Specific Microperimetry.

Structure-Function Correlation in Diabetic Retinal Disease using Innovative High-Resolution Imaging and Lesion-Specific Microperimetry. - MIND-study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00036499

Enrollment

200

Registered

2025-05-30

Start date

2025-07-02

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E11.30 E10.30

Interventions

Group 1: Diabetics with or without diabetic retinopathy / maculopathy Multimodality imaging using conventional SD-OCT, OCTA, MPOD and High-resolution OCT is performed every 3 to 6 months for 3 years

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Consenting patients with type I/II diabetes mellitus

Exclusion criteria

Exclusion criteria: Other previous retinal diseases (age-related macular degeneration, glaucoma, retinal vascular occlusion) and/or inadequate quality of imaging

Design outcomes

Primary

Measure	Time frame
- Measurement of retinal sensitivity in areas of the biomarker DRIL (disorganisation of the retinal inner layers) using lesion-specific microperimetry - Correlation of DRIL lesions to the optical density of the macular pigment (MPOD) - Longitudinal detection of vascular perfusion in DRIL lesions	—

Secondary

Measure	Time frame
- Correlation of MPOD and carotenoid intake - Correlation of HbA1c with MPOD and vascular perfusion - Comparison of perfusion, MPOD and retinal sensitivity of diabetics with and without DRIL lesions	—

Countries

Germany

Contacts

Public ContactThomas Ach

Universitäts-Augenklinik Bonn

thomas.ach@ukbonn.de+4922828715613

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026