Q20.3
Conditions
Interventions
Group 1: Adult EMAH patients who underwent an atrial switch operation with D-transposition of the great arteries in childhood at the paediatric cardiac surgery department of the University Hospital of
Sponsors
Universitätsklinikum Aachen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adult EMAH patients who underwent an atrial switch operation with D-transposition of the great arteries in childhood at the paediatric cardiac surgery department of the University Hospital of RWTH Aachen and, if applicable, external centres
Exclusion criteria
Exclusion criteria: Persons who are deprived of their liberty on the basis of an official order or a court order or authorisation - There are no other general exclusion criteria for the cohort register. - Persons deprived of their liberty on the basis of an official order or a court order or authorisation - There are no other general exclusion criteria for the cohort register. There may be clinical contraindications for individual components of the study that lead to certain examinations not being carried out: - In the case of pregnancy (verbal enquiry at the time of invitation and study inclusion), inclusion in the study is currently not possible. - Inclusion in the study may be possible at a later date. - If the patient has already been included in the observational study, an examination outside the scope of the cohort study may be carried out during the pregnancy for clinical reasons. Individual medical care independent of the study is of course also possible at any time during pregnancy or breastfeeding. - Patients with contraindications to an MRI examination (e.g. non-MRI-capable pacemaker or defibrillator, certain metallic implants, severe claustrophobia) will not undergo an MRI examination. - Patients with contraindications to the use of MRI contrast agents (severe renal insufficiency with a glomerular filtration rate below 30 ml/min, known gadolinium contrast agent allergy) are not given an MRI contrast agent. If necessary, an MRI examination without contrast medium is advisable. This will be discussed with you individually. - Patients with contraindications to adenosine/regadenoson or dobutamine stress (e.g. high-grade aortic stenosis, uncontrolled high blood pressure, acute or unstable angina pectoris symptoms) will not undergo a stress examination with the respective stress medication. Patients with contraindications to a CT contrast agent examination (known allergy to iodine-containing X-ray contrast agents, impaired kidney function, hyperthyroidism) will not undergo a CT examination. - Patients with physical disabilities or other illnesses that make a spiroergometric examination impossible will not undergo a spiroergometric examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| no clinical endpoint: On the basis of a homogeneous patient group in the 4th and 5th decade of life after atrial reversal surgery after Senning for dTGA, the planned comprehensive clinical follow-up examination enables an assessment of the therapy concept in the long-term course as well as the assessment of cardiac risk and quality of life for patients in advancing adulthood | — |
Countries
Germany
Contacts
Public ContactSusanne Recker
Universitätsklinikum Aachen
Outcome results
None listed