Efficacy evaluation of a mind-body medicine-based health promotion course for patients with multiple sclerosis - A mixed-methods study with a randomised controlled trial

Efficacy evaluation of a mind-body medicine-based health promotion course for patients with multiple sclerosis - A mixed-methods study with a randomised controlled trial - BERN MS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00036453

Enrollment

Registered

2025-04-07

Start date

2025-04-10

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G35

Interventions

Group 1: The BERN (Behaviour, Exercise, Relaxation, Nutrition) mind-body intervention aims to promote general quality of life and to reduce stress. BERN is an eight-week health promotion course in whi

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Expanded Disability Scale max. 8 Mini-Mental-Status-Test min. 20 Willigness to change German speaking

Exclusion criteria

Exclusion criteria: Expanded Disability Scale more than 8 Mini-Mental-Status-Test 19 or lower No interest in change Non-German speaking

Design outcomes

Primary

Measure	Time frame
Subjective improvement of quality of life The Perceived Stress Scale, the 12-Item Short Form Survey, the Freiburg Mindfulness Inventory and the Social Support Survey are expected to be integrated in the questionnaire. The aim is to include 60 MS patients in the RCT. The inclusion criteria are: MS diagnosis, age of majority, a score of max. 8 on the Expanded Disability Status Scale and a score of min. 20 on the Mini-Mental Status Test. The course is accompanied by a survey with three measurement points. The first data collection (T0) takes place at the beginning of the intervention. The second survey (T1) takes place after completion of the course and the third twelve weeks after the end of the course (T2). The control group completes T0, T1 and T2 and receives the usual medical and therapeutic treatment.	—

Measure

Time frame

Subjective improvement of quality of life The Perceived Stress Scale, the 12-Item Short Form Survey, the Freiburg Mindfulness Inventory and the Social Support Survey are expected to be integrated in the questionnaire. The aim is to include 60 MS patients in the RCT. The inclusion criteria are: MS diagnosis, age of majority, a score of max. 8 on the Expanded Disability Status Scale and a score of min. 20 on the Mini-Mental Status Test. The course is accompanied by a survey with three measurement points. The first data collection (T0) takes place at the beginning of the intervention. The second survey (T1) takes place after completion of the course and the third twelve weeks after the end of the course (T2). The control group completes T0, T1 and T2 and receives the usual medical and therapeutic treatment.

—

Secondary

Measure	Time frame
Stress reduction	—

Countries

Germany

Contacts

Public ContactTobias Esch

Universität Witten/Herdecke

igvf@uni-wh.de+49 2302 / 926-847

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026