K10.28
Conditions
Interventions
Group 1: Patients with medication-related osteonecrosis of the jaw are interviewed with the questionnaires OHP-G53 and MRONJ-QoL ( two interview times: pre- & postoperative)
Sponsors
Klinik und Poliklinik für Mund-, Kiefer- und Plastische Gesichtschirurgie des Universitätsklinikums Bonn
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: -Ability to consent and written consent to participate in the study - Diagnosed MRONJ -Consent to surgical therapy -Ability to meet the requirements of the study
Exclusion criteria
Exclusion criteria: -Lack of consent -Recurrence or new lesion after surgery -dementia patients or patients with other cognitive impairments who are unable to consent to the study - Patients who do not agree to participate in the study for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the subjective health-related quality of life of patients with medication-related necrosis of the jaw (MRONJ) using the questionnaires OHIP-G53 (Oral Health Impact Profile) and MRONJ-QoL (medication-related osteonecrosis of the jaw) preoperatively and 4-6 weeks after surgical rehabilitation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in the results of questionnaires -With regard to gender and age -Regarding the extent, stage according to AAOMS and the number and location of necrosis(es) -Regarding the individual risk profile -Depending on the dental findings or the possible dentures - Depending on jaw necrosis-inducing medication (bisphosphonates o. Denosumab), dose, duration -Depending on underlying diseases or the existing malignant tumor, (bone) metastases or osteoporosis -Depending on objective therapeutic success (downstaging) | — |
Countries
Germany
Contacts
Public ContactBenedict Jürgensen
Klinik und Poliklinik für Mund-, Kiefer- und Plastische Gesichtschirurgie des Universitätsklinikums Bonn
Outcome results
None listed