Adherence to topical steroids in patients with CRSwNP Under Ongoing biologic therapy

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00036396

Enrollment

Registered

2025-03-13

Start date

2024-10-03

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J33

Interventions

Group 1: cohort of 40 adult CRSwNP patients undergoing biologic therapy (therapy initiated at least 6 months ago)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Severe chronic rhinosinusitis with nasal polyps (CRSwNP) according to EPOS/EUFOREA criteria Ongoing biologic therapy (at least 6 months) according to German regulatory approval Written informed consent for study participation

Exclusion criteria

Exclusion criteria: Lack of consent for participation

Design outcomes

Primary

Measure	Time frame
Determination of the adherence rate in the application of topical steroids (e.g., mometasone nasal spray) in patients with CRSwNP undergoing biologic therapy after three and six months	—

Secondary

Measure	Time frame
- Factors Influencing Adherence: Analysis of demographic and clinical factors (e.g., age, disease duration, prior surgeries, biologic therapy success) that may impact adherence. - Objective vs. Self-Reported Adherence: Comparison of actual steroid consumption with patient-reported usage. - Adherence and Treatment Success: Correlation between adherence rates and objective treatment outcomes based on EUFOREA criteria. - Impact of Study Participation: Assessment of whether study involvement influences patient adherence over time.	—

Measure

Time frame

- Factors Influencing Adherence: Analysis of demographic and clinical factors (e.g., age, disease duration, prior surgeries, biologic therapy success) that may impact adherence. - Objective vs. Self-Reported Adherence: Comparison of actual steroid consumption with patient-reported usage. - Adherence and Treatment Success: Correlation between adherence rates and objective treatment outcomes based on EUFOREA criteria. - Impact of Study Participation: Assessment of whether study involvement influences patient adherence over time.

—

Countries

Germany

Contacts

Public ContactLisa Knipps

St. Josefs-Hospital Hagen

lisa.knipps@uni-wh.de+4923318059254

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026