F32.1 F32.2 F33.1 F33.2 F32.0 F33.0
Conditions
Interventions
Group 1: Group: Depression, Age 60+ years
Intervention: 2 tDCS sessions (20 min, 2 mA, active and sham)
Electrode placement (10-20 EEG system):
- Anode: left DLPFC (F3)
- Cathode: ventromedial P
Sponsors
Otto-von-Guericke Universität Magdeburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Ability and willingness to consent to the study Age: = 60 years (or 18-25) Primary clinical diagnosis of a depressive episode (ICD-10: F32.1, F32.2, F33.1, F33.2)
Exclusion criteria
Exclusion criteria: Acute suicidality (clinical impression) Other relevant psychiatric disorders: Bipolar disorder, psychosis or schizophrenia, addiction/substance abuse Epilepsy/previous epileptic seizures Family history of epileptic seizures Mild cognitive impairment Neurodegenerative diseases Past or present neurological disorders or head surgeries Implants: Cochlear implant, pacemaker, deep brain stimulation, vagus nerve stimulation Acute dermatological condition of the scalp Pregnancy or breastfeeding Non-German speaking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Performance gains in working memory task (N-Back) with affective component conducted during stimulation (online). | — |
Secondary
| Measure | Time frame |
|---|---|
| Pre- and post-stimulation assessments (offline): - Acute mood assessment (PANAS; Positive and Negative Affect Schedule) - Near-transfer: Visuospatial working memory task - Emotional biases: Dot-probe task with emotional faces - Far-transfer: Inhibitory control (Go/NoGo) | — |
Countries
Germany
Contacts
Public ContactClaudia Preuschhof
Otto-von-Guericke Universität Magdeburg
Outcome results
None listed