Effect of anti-pigment products on melanin in the epidermis in vivo

Effect of anti-pigment products on melanin in the epidermis in vivo - Anti-Pigment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00036376

Enrollment

Registered

2025-03-13

Start date

2025-04-17

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

L81.0

Interventions

Group 1: Application of thiamidol-containing cream twice daily for 8 weeks. Examinations with multiphoton tomography and laser scanning microscopy at the beginning, after 4 and 8 weeks. Group 2: Appli

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - who have pigment spots on the arms or décolleté - who have little hair on the areas to be measured - who have been informed about the aims of the study and the nature of the examinations - who have given their written informed consent to participate.

Exclusion criteria

Exclusion criteria: - children - Persons who have not given their informed consent in writing - Persons who cannot make decisions on their own responsibility

Design outcomes

Primary

Measure	Time frame
Change in melanin detectable by two-photon microscopy.	—

Secondary

Measure	Time frame
Proof of the change at different depths.	—

Countries

Germany

Contacts

Public ContactMartina Meinke

Charité – Universitätsmedizin Berlin

martina.meinke@charite.de+4930450518235

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026