Motor impairment of one side of the body after stroke I69 G81
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: First-time stroke, chronic stage (at least six months after the stroke), permanently reduced mobility of an upper limb, physical and mental suitability
Exclusion criteria
Exclusion criteria: Moderate to severe aphasia, apraxia, neglect, other serious physical or mental illness in addition to stroke, complete loss of mobility of an upper limb, unsuitability for MRI scans (metallic objects in the body, pregnancy, claustrophobia), sleep deprivation (< than four hours sleep), drug use, use of medication affecting the central nervous system, simultaneous participation in another study on stroke
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analysis of functional brain connectivity at rest before and during MI-NF training using coherence analysis of resting-state EEG data. | — |
Secondary
| Measure | Time frame |
|---|---|
| Investigation of EEG power, event-related desynchronization (ERD), and lateralization of brain activity during MI-NF training; Analysis of functional connectivity and brain activity using fMRI; Assessment of changes in motor performance through standardized tests (ARAT, mFMA-UE) and maximal grip strength; analysis of upper limb movements using IMU sensors and RGB-D cameras; Examination of the correlation between changes in motor performance and neural activity/connectivity; Comparison of motor and cognitive test results before and after MI-NF training; Investigation of the relationship between motor assessment (e.g., ARAT, mFMA-UE, grip strength) and analyzed movement data of the upper limbs. | — |
Countries
Germany
Contacts
Carl von Ossietzky Universität Oldenburg