P35.8
Conditions
Interventions
Group 1: Children who were exposed to infection during pregnancy through their mother's parvovirus B19 infection and who showed signs of fetal anemia should be examined by a pediatric cardiologist in
Sponsors
Universitätsklinikum Bonn
Eligibility
Sex/Gender
All
Age
No minimum to 11 Years
Inclusion criteria
Inclusion criteria: Parvovirus B19 infection during Pregnancy
Exclusion criteria
Exclusion criteria: Withdrawal of consent, No Parvovirus B19 infection during Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| No endpoints in the conventional sense are defined. The aim of the study is to investigate the influence of a parvovirus B19 infection during pregnancy on fetal outcome. In particular, the influence of the time of infection and the severity of the anemia on possible long-term neurological and cardiological consequences will be investigated. For this purpose, prenatal data from pregnant women with parvovirus B19 infection will be evaluated retrospectively. This will be followed by a prospective follow-up examination of the affected children at the ages of 2, 6 and 10 years, in which cognitive, motor and neurological developmental aspects will be recorded using the Bayley III test (2 years) and the WISC-V test (6 and 10 years). In addition, a pediatric cardiology examination using an ECG and detailed ultrasound of the heart will be carried out in the first year of life in order to identify possible long-term cardiological abnormalities. | — |
Countries
Germany
Contacts
Public ContactMarcel Habeth
Universitätsklinikum Bonn
Outcome results
None listed