Skip to content

Neurophysiological Changes associated with Treatment of Depression in Youth

Neurophysiological Changes associated with Treatment of Depression in Youth - Depression, Adolescents, Emotion regulation, Emotion recognition

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00036113
Enrollment
52
Registered
2026-05-29
Start date
2026-08-17
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F32.1

Interventions

Group 1: Adolescents with depressive symptoms presenting for their first clinical referral will undergo EEG and eye-tracking assessments while performing an emotional recognition task. The same measur

Sponsors

Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters, Uniklinik der RWTH Aachen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
11 Years to 17 Years

Inclusion criteria

Inclusion criteria: • Age between 11 and 17 years • A confirmed diagnosis of depression; there must be no comorbid diagnosis of a neuropsychiatric developmental disorder, such as autism or ADHD • An IQ of at least average

Exclusion criteria

Exclusion criteria: • Acute suicidal ideation • Use of benzodiazepines • Current or past neurological disorders • Insufficient knowledge of German Additional exclusion criteria for eye tracking • Nystagmus • Strabismus • Uncorrected visual impairment • Use of stimulants • Use of sedatives

Design outcomes

Primary

MeasureTime frame
Can diagnostic biomarkers be identified in resting-state source EEG that distinguish a severe course of depression from a mild one?

Secondary

MeasureTime frame
Do these biomarkers have predictive value regarding the success of inpatient treatment for children and adolescents?

Countries

Germany

Contacts

Public ContactMichael Siniatchkin

Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters, Uniklinik der RWTH Aachen

msiniatchkin@ukaachen.de+492418088737

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026