Perioperative bleeding during double lung transplantation in patients with extracorporeal membrane oxygenation as bridge-to-transplant: a retrospective study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00036086

Enrollment

150

Registered

2025-02-11

Start date

2025-03-01

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Z94.2

Interventions

Group 1: In double-lung transplanted patients with preoperative extracorporeal membrane oxygenation as a bridge-to-transplant, data on the bleeding rate, blood product and coagulation product therapy

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: * ICU Admission prior to lung transplantation

Exclusion criteria

Exclusion criteria: * Multiorgan transplantation * Single lung transplantation * Double-lung transplantation with cardiopulmonary bypass

Design outcomes

Primary

Measure	Time frame
Number of red blood cell concentrates during double-lung transplantation	—

Secondary

Measure	Time frame
* Number of "fresh frozen plasma" units administered during double-lung transplantation * Number of platelet concentrates administered during double-lung transplantation * Cumulative dose of fibrinogen concentrate during double-lung transplantation * Cumulative dose of four-factor prothrombin complex concentrate administered during double-lung transplantation * Number of red blood cell concentrates within 24 hours postoperatively * Number of "fresh frozen plasma" units administered within 24 hours postoperatively * Number of platelet concentrates administered within 24 hours postoperatively * Cumulative dose of fibrinogen concentrate within 24 hours postoperatively * Cumulative dose of four-factor prothrombin complex concentrate administered within 24 hours postoperatively * Cumulative chest tube output up to 24 hours postoperatively * Surgical revision in the operating room within 24 hours after double-lung transplantation * Surgical revision in the operating room within 5 days after double-lung transplantation	—

Measure

Time frame

* Number of "fresh frozen plasma" units administered during double-lung transplantation * Number of platelet concentrates administered during double-lung transplantation * Cumulative dose of fibrinogen concentrate during double-lung transplantation * Cumulative dose of four-factor prothrombin complex concentrate administered during double-lung transplantation * Number of red blood cell concentrates within 24 hours postoperatively * Number of "fresh frozen plasma" units administered within 24 hours postoperatively * Number of platelet concentrates administered within 24 hours postoperatively * Cumulative dose of fibrinogen concentrate within 24 hours postoperatively * Cumulative dose of four-factor prothrombin complex concentrate administered within 24 hours postoperatively * Cumulative chest tube output up to 24 hours postoperatively * Surgical revision in the operating room within 24 hours after double-lung transplantation * Surgical revision in the operating room within 5 days after double-lung transplantation

—

Countries

Austria

Contacts

Public ContactMarion Wiegele

Medizinische Universität Wien

marion.wiegele@meduniwien.ac.at+43 1 40400 41020

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026