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Device-associated ventriculitis in intensive care patients

Device-associated ventriculitis in intensive care patients - ALERT

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00036075
Enrollment
200
Registered
2025-02-07
Start date
2025-01-31
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Z98.2

Interventions

Group 1: All patients of the surgical intensive care unit of the Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, who received an EVD between 1 January 2019 and 31 December 2023. A total
100 patients before and 100 patients after application of the SOP.

Sponsors

Charité Universitätsmedizin Berlin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients of the surgical intensive care unit of the Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, who received an EVD between 1 January 2019 and 31 December 2023.

Exclusion criteria

Exclusion criteria: • External Ventricular Drain < 3 days • Pre-existing CNS infection

Design outcomes

Primary

MeasureTime frame
Reduction in infection rate following implementation of a bundle of interventions to manage inserted EVD and detect ventriculitis through more reliable diagnostic criteria

Secondary

MeasureTime frame
-Reduction in antibiotic consumption - Reduction in empirical use of antibiotics - Antibiotic-free days/duration and cumulative dose of antibiotic therapy - Reduction in false positive diagnosis of ventriculitis - Adherence to bundle of measures and algorithm - Reduction in length of stay in intensive care unit - Reduction in mortality

Countries

Germany

Contacts

Public ContactMichaela Danassis

Charité Universitätsmedizin Berlin

michaela.danassis@charite.de+49 30 450 651531

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026