Neurogenic dysphagia due to PD, ALS, IBM and MG.
Conditions
Interventions
Group 1: In patients with PD, ALS, IBM or MG, a brief logopedic history, a FEES and the BoDyS (Ziegler et al., 2018) are carried out once.
Sponsors
Universität zu Lübeck
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: There is an indication for a FEES. For this study, there is an indication for a FEES if dysphagia is suspected by the attending physician or if the diagnosis of dysphagia has already been confirmed by a clinical swallowing examination (KSU), FEES or videofluoroscopy (VFSS) and a re-evaluation of swallowing is indicated.
Exclusion criteria
Exclusion criteria: - Contraindications for FEES (e.g. unstable general condition, acute cardiac symptoms, vomiting) - Stress tolerance/attention < 60 min - Other neurological diseases that can cause dysphagia/dysarthria - Mutism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoints are symptoms of neurogenic dysphagia (such as akinesia and tremor) due to PD, ALS, IBM and MG, which are indicative of specific pathomechanisms (central/spastic or peripheral/flaccid paresis, hypo- or hyperkinetic movement disorder) and which should occur with varying frequency depending on the underlying disease. These are measured once using FEES. Other primary endpoints are symptoms of dysarthria (such as akinesia and tremor) due to PD, ALS, IBM and MG. These are measured once using the BoDyS (Ziegler et al., 2018). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measure is the agreement of symptom ratings by two independent raters on 3-4 randomly selected FEES videos from each clinical picture. | — |
Countries
Germany
Contacts
Public ContactValentine Silberling
Universität zu Lübeck
Outcome results
None listed