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Pupillometry in the Emergency Room For Evaluation, Control and Treatment of Coma of Unknown Etiology

Pupillometry in the Emergency Room For Evaluation, Control and Treatment of Coma of Unknown Etiology - PERFECT CUE

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00036028
Enrollment
500
Registered
2025-01-29
Start date
2025-02-15
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R40.2

Interventions

Group 1: Inclusion of Patients with coma who present to the emergency department The study will collect data from automated pupillometry at the time of admission to the emergency department as well a

Sponsors

Ludwig Maximilians Universität München
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: quantitative impairment of consciousness (Glasgow Coma Svale Score < 15), QP performed within 3 hours of admission, inclusion under emergency criteria possible

Exclusion criteria

Exclusion criteria: Eye injury or known eye disease, death on admission or within 3 hours after admission, impossibility of further diagnostic clarification (e.g. transfer to another clinic before a definitive diagnosis is made)

Design outcomes

Primary

MeasureTime frame
The study examines whether a prediction regarding a definitive diagnosis can be made based on pupillometry data. The specific question is whether the data collected in pupillometry can differentiate whether there is a primary neurogenic cause with or without a structural brain lesion.

Secondary

MeasureTime frame
Can pupillometry be used to predict death or severe disability (as measured by a modified Rankin Scale (mRS)) at discharge from acute hospital?

Countries

Germany

Contacts

Public ContactMatthias Klein

Ludwig-Maximilians Universität

matthias.klein@med.uni-muenchen.de+49894400711567

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026