Progression of cavernous transformed non-cirrhotic portal vein thrombosis (KAVERNOM study)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00036003

Enrollment

200

Registered

2026-07-08

Start date

2025-09-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I81

Interventions

Group 1: Retrospective collection of clinical data/events (see endpoints) from patients with cavernous transformation of non-cirrhotic portal vein thrombosis

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult patients with a diagnosis of cavernous transformed non-cirrhotic portal vein thrombosis

Exclusion criteria

Exclusion criteria: Patients unable to give informed consent Patients with non-cirrhotic portal vein thrombosis without cavernous transformation Patients with cirrhotic portal vein thrombosis Patients with non-cirrhotic portal vein thrombosis with cavernous transformation who have achieved portal vein recanalization through specific (conservative or interventional) therapy

Design outcomes

Primary

Measure	Time frame
Primary endpoint is the occurrence of variceal bleeding Since this is a retrospective study, this endpoint will be determined based on digital patient records as part of the data collection process.	—

Secondary

Measure	Time frame
Varices Ascites Hypersplenism portal Cholangiopathy Mortality	—

Countries

Germany

Contacts

Public ContactMichael Schultheiß

Uniklinik Freiburg

michael.schultheiss@uniklinik-freiburg.de+49 761 27034010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026