Oral doxycycline vs. penicillin G or ceftriaxone in the therapy of neurosyphilis - pilot study of a multicentre open-label randomized intervention study

Oral doxycycline vs. penicillin G or ceftriaxone in the therapy of neurosyphilis - pilot study of a multicentre open-label randomized intervention study - DOPAMINE-Pilot

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00035966

Enrollment

Registered

2025-01-22

Start date

2025-03-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A52.3

Interventions

Group 1: Retrospective Data Collection: For the retrospective data collection, anonymized cases of neurosyphilis from the past 12 months will be documented at the centers based on data already col

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with neurosyphilis

Exclusion criteria

Exclusion criteria: Lack of informed consent

Design outcomes

Primary

Measure	Time frame
Description of the epidemiology, comorbidities, comedications, microbiological findings, and therapy (antibiotic combination therapy) of patients with neurosyphilis.	—

Secondary

Measure	Time frame
Patient based barriers and motivators for study participation	—

Countries

Germany

Contacts

Public ContactJohannes Camp

Universitätsklinikum Freiburg

johannes.camp@uniklinik-freiburg.de+4976127018190

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026