I69
Conditions
Interventions
Group 1: Experimental group: Stroke patients receive an additional four weeks of training with a soft hand exoskeleton. Before and after this, an MRI scan with functional and structural images as well
Sponsors
Institut für Kognitive Systeme, Technische Universität München
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: - Patients with a stroke - Paralyzed hand with partial remaining function e.g., hemiparesis with predominantly arm-/hand weakness - MRI compatibility - Ability to execute the training - Sufficient knowledge of German or English - Ability to understand, follow the instructions and give written informed consent
Exclusion criteria
Exclusion criteria: - Severe aphasia, neglect, tremor, or spasticity - Severe cognitive impairment - Degrees of freedom of the finger joints and wrist must not be otherwise restricted (e.g., no arthritis, gout or other orthopedic, rheumatologic and neurological diseases that inhibit movement or do not allow pain-induced movement) - Hand deformities and wounds, amputation, severe pain in affected limb, no EMG activity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| functional brain activation during the MRI task (grasping a cylinder with and without exoskeleton support) | — |
Secondary
| Measure | Time frame |
|---|---|
| - further functional/structural brain alterations (resting state, DTI) - hand motor performance (ARAT, FMA, BBT, grip strength) - psychological characteristics (SUS, NASA-TLX, SF-12, VAS scales, Sense of Agency measure, HAM-D/PHQ-9) | — |
Countries
Germany
Contacts
Public ContactKathrin Koch
Klinikum rechts der Isar, TUM-NIC
Outcome results
None listed