Genetic investigation in idiopathic intracranial hypertension

Genetic investigation in idiopathic intracranial hypertension - Gen-IIH

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00035932

Enrollment

Registered

2025-01-20

Start date

2025-01-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G93.2

Interventions

Group 1: Patients with idiopathic intracranial hypertension according to the revised Friedman criteria, in whom clinical evidence suggests a genetic predisposition, will undergo genetic testing via wh

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Confirmed IIH diagnosis according to the revised Friedman criteria & indications of a genetic predisposition (normal weight patients, male individuals, familial clustering, fulminant course).

Exclusion criteria

Exclusion criteria: IIH without papilledema (IIHWOP), possible IIH, secondary intracranial hypertension

Design outcomes

Primary

Measure	Time frame
pathogenic variants	—

Secondary

Measure	Time frame
candidate genes & variants of unknown significance	—

Countries

Germany

Contacts

Public ContactTheresia Knoche

Charité Universitätsmedizin Berlin - Klinik für Neurologie

theresia.knoche@charite.de030450660078

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026