Evaluation of the correlation of plasma volume status (PVS) to the haemodynamic parameters of transpulmonary thermodilution with continuous pulse contour analysis (PiCCO). A retrospective data analysis.

Evaluation of the correlation of plasma volume status (PVS) to the haemodynamic parameters of transpulmonary thermodilution with continuous pulse contour analysis (PiCCO). A retrospective data analysis. - PVSvsPiCCO

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00035926

Enrollment

800

Registered

2025-01-17

Start date

2024-08-22

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients requiring intensive care without precise reasons. All patients with extended haemodynamic monitoring by PiCCO are included.

Interventions

Group 1: Retrospective analysis of all patients from 01/2020 to 03/2024 who were treated in one of the anaesthesiologically managed intensive care units at Mainz University Hospital with extended haem

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Period from 01/2020 to 03/2024

Exclusion criteria

Exclusion criteria: Incomplete data acquisition, acquisition of other haemodynamic parameters that were not recorded with PiCCO, Pre-existing atrial fibrillation, No invasive mechanical ventilation

Design outcomes

Primary

Measure	Time frame
Assessment of the correlation of the Plasma Volume Status values with the haemodynamic parameters of the PiCCO measurement (stroke volume variance, global end-diastolic volume). These values are recorded at every point in the calibration of the PiCCO system (usually every 8 hours or at shorter intervals if there is an acute change in the patient's condition). All data records of the intensive care stay from admission to discharge are recorded.	—

Measure

Time frame

Assessment of the correlation of the Plasma Volume Status values with the haemodynamic parameters of the PiCCO measurement (stroke volume variance, global end-diastolic volume). These values are recorded at every point in the calibration of the PiCCO system (usually every 8 hours or at shorter intervals if there is an acute change in the patient's condition). All data records of the intensive care stay from admission to discharge are recorded.

—

Secondary

Measure	Time frame
Assessment of plasma volume status values in the event of changes in stroke volume, cardiac index and lactate. Changes in PVS in the event of Hb-relevant haemorrhages. Change in PVS if renal replacement therapy is required.	—

Countries

Germany

Contacts

Public ContactKatharina Hentschel-Monteiro

Universitätsmedizin Mainz, Klinik für Anästhesiologie, Studienzentrum Anästhesie

katharina.hentschel@unimedizin-mainz.de06131 176755

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 29, 2026