R54
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Patients of the anesthesia intensive care unit of the University Medical Center Mainz between 01.01.-31.12.2020 - ICU stay of at least 3 days (72 hours)
Exclusion criteria
Exclusion criteria: - ICU stay <72 hours - Incomplete admission scores (SAPS, TISS28 and SOFA) for the first 72 hours of the respective ICU stay
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inter-rater reliability of the Clinical Frailty Scale (CFS), which is determined discretely (scale value 1-9) and categorically (A = non frail = CFS 1-3; B = vulnerable = CFS =4; C = frail = CFS >4) by 3 independent raters using defined sources to be used | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary efficacy data with influence on mortality (1. ICU mortality, 2. 30-day mortality): Patient age, SOFA, TISS28, SAPS, Charlson Comorbidity Index (CCI), case-mix score of disease severity, ICU bed days, hospital bed days, ventilator hours, readmission to ICU 48h, COVID, Was an advance directive in place?, Was a DNR agreement in place? BMI, ASA (first ASA score; only available for surgical patients), surgery, organ replacement in ICU (invasive ventilation, renal replacement therapy, transfusion), complications in ICU (re-intubation, CPR, ICB, stroke), laboratory parameters in ICU (lactate, PCT) - Treatment goal discussions: Did discussions take place regularly, promptly, interdisciplinary, interprofessional? 1. when was the first discussion, 2. when was therapy limitation/termination, 3. how long did patients remain in the ICU in this case? Correlations/dependencies with independent variables (e.g. tumor yes/no, age 65-80 vs. >80, CFS fit vs. frail, SOFA severe vs. less severely ill, organ insufficiency) | — |
Countries
Germany
Contacts
Klinik für Anästhesiologie, Universitätsmedizin Mainz