Retrospective Analysis of the Maximal Aortic valve Cusp Separation (MACS) as a screening tool for moderate to severe aortic valve stenosis

Retrospective Analysis of the Maximal Aortic valve Cusp Separation (MACS) as a screening tool for moderate to severe aortic valve stenosis - MACS-AS

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00035857

Enrollment

424

Registered

2025-02-14

Start date

2025-01-07

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I35.0

Interventions

Group 1: Patients with aortic stenosis as proven by an transthoracic echocardiogram (TTE) in the cardiology echo lab, Charité Campus Virchow Klinikum.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnosis of aortic valve stenosis (mild, moderate, or severe) by transthoracic echocardiography performed by an expert in echocardiography.

Exclusion criteria

Exclusion criteria: 1) Age under 18 years. 2) History of aortic valve replacement (prosthetic valve or homograft) or transfemoral aortic valve intervention (TAVI or balloon valvuloplasty). 3) Imaging quality reported as: "poor" or "insufficient".

Design outcomes

Primary

Measure	Time frame
MACS and its diagnostic value in differentiating mild from significant (moderate-to-severe) aortic stenosis.	—

Countries

Germany

Contacts

Public ContactLeo Fabig

Charité Universitätsmedizin Berlin, Klinik für Anästhesiologie und Intensivmedizin

leo.fabig@charite.de+49 030 450 551102

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026