Acute Management and Outcomes after ischemic STroke in patients with known Atrial Fibrillation

Acute Management and Outcomes after ischemic STroke in patients with known Atrial Fibrillation - MOST-AF

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00035815

Enrollment

1200

Registered

2025-01-03

Start date

2025-02-01

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I63

Interventions

Group 1: Acute stroke patients with known atrial fibrillation receive standard care. Data on acute management and past medical history is extracted from routine clinical notes. Data on 90-day outcomes

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Clinical diagnosis of acute ischemic stroke Stroke symptom onset within 24 hours prior to presentation Known diagnosis of atrial fibrillation Treatment on a certified German Stroke Unit or Neuro-Intensive Care Unit

Exclusion criteria

Exclusion criteria: First diagnosis of atrial fibrillation in-hospital Participation in a randomized acute stroke trial with concealed treatment allocation

Design outcomes

Primary

Measure	Time frame
Functional outcome (modified Rankin Scale) after 3 months	—

Secondary

Measure	Time frame
Symptomatic intracranial hemorrhage (mSITS-MOST) within 36 hours	—

Countries

Germany

Contacts

Public ContactEckhard Schlemm

Universitätsklinikum Hamburg-Eppendorf

e.schlemm@uke.de+4915222898447

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026