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Retrospective evaluation of the technical and clinical value of photon-counting computed tomography in routine clinical practice

Retrospective evaluation of the technical and clinical value of photon-counting computed tomography in routine clinical practice

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00035784
Enrollment
10000
Registered
2024-12-20
Start date
2024-12-19
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Diseases: Steatosis hepatis, liver fibrosis

Interventions

Group 1: Retrospective inclusion of patients who have received imaging studies using the Photon Counting Detector CT since 01.01.2021.

Sponsors

Klinik für Diagnostische und Interventionelle Radiologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Retrospective inclusion of patients who have undergone imaging with the photon-counting detector CT since January 1, 2021.

Exclusion criteria

Exclusion criteria: No specific additional exclusion of patients is planned to avoid biasing the analysis for patient subgroups.

Design outcomes

Primary

MeasureTime frame
Evaluation of image quality and tissue resolution in photon-counting computed tomography (PCD-CT) based on subjective criteria (Likert scale) and objective measurements (Signal-to-Noise Ratio, Contrast-to-Noise Ratio), aiming to enhance diagnostic accuracy while reducing radiation exposure.

Secondary

MeasureTime frame
Collection and analysis of material decomposition data (e.g., calcium, iodine, fat, water) in tissues to establish new biomarkers for diseases such as liver steatosis, fibrosis, and musculoskeletal pathologies, and to assess their potential clinical benefits.

Countries

Germany

Contacts

Public ContactStephan Rau

Klinik für Diagnostische und Interventionelle Radiologie

stephan.rau@uniklinik-freiburg.de+49 172 7563532

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026