Determinants of open-label placebo administration in emotional stress: a randomized controlled trial

Determinants of open-label placebo administration in emotional stress: a randomized controlled trial - OLPimag

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00035720

Enrollment

140

Registered

2024-12-16

Start date

2024-12-16

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emotional Distress

Interventions

Group 1: Open-label placebo self-administered (single dose of nasal spray with NaCl labelled as placebo), before rating of negative pictures and after measurements of mood and anxiety (PANAS and STAI

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: None.

Exclusion criteria

Exclusion criteria: Psychiatric or neurological history, pregnancy

Design outcomes

Primary

Measure	Time frame
Emotional Distress, measured before and after treatment, measured by ratings of negative pictures of IAPS-database (Lang et al., 2008).	—

Countries

Germany

Contacts

Public ContactMichael Schaefer

Medicalschool Berlin

michael.schaefer@medicalschool-berlin.de+49 30 76 68 37 53-63

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026