Fixed screw-retained full-arch prosthesis, monolithic zirconia superstructure cemented to titanium substructure: a cohort study

Fixed screw-retained full-arch prosthesis, monolithic zirconia superstructure cemented to titanium substructure: a cohort study - Full-arch

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00035707

Enrollment

Registered

2025-03-05

Start date

2025-07-23

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Edentulous patients K08.1 K08.9

Interventions

Group 1: Patients who received a fixed screw-retained full arch prosthesis fabricated with a monolithic zirconia superstructure cemented to a titanium substructure by clinicians of the clinic for reco

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Patients who received an implant retained full-arch prosthesis with a monolithic zirconia superstructure extrorally cemented to a customized titanium bar. - Prosthesis has to be retained by 4 implants

Exclusion criteria

Exclusion criteria: - Unable to follow the study procedures - Pregnant/lactating women

Design outcomes

Primary

Measure	Time frame
Success of implant prosthesis. This is measured as no reported or observed complications since insertion (e.g. implant failure, periimplantitis, fracture of the prosthesis...). The complications that have (or have not) occurred are checked at each visit (1 year, 3 years and 5 years). At the end, the primary endpoint is understood as the number of complications measured in the period from the delivery of the prosthesis to the 5-year follow-up.	—

Measure

Time frame

Success of implant prosthesis. This is measured as no reported or observed complications since insertion (e.g. implant failure, periimplantitis, fracture of the prosthesis...). The complications that have (or have not) occurred are checked at each visit (1 year, 3 years and 5 years). At the end, the primary endpoint is understood as the number of complications measured in the period from the delivery of the prosthesis to the 5-year follow-up.

—

Secondary

Measure	Time frame
The secondary endpoints are measured at each visit (1y, 3y, 5y after providing the patient with the prosthesis). - Implant and prosthetic survival - Biological parameters (marginal bone level, bleeding on probing, plaque index, probing depth, width keratinized mucosa, biological complications) at implant site - Technical parameters (wear of the restoration / antagonist) - Maintenance costs - Subjective evaluation of food impaction and plaque accumulation under the prosthesis (Before and after staining with methylene blue) - PROMS: patient satisfaction; ease of oral hygiene (general/specifc implant related); brushing discomfort - Aesthetics: Overall esthetic appearance (OES) - Soft tissue support (Facial analysis with facescans; mm) - Vestibular depth at implant site - Fit accuracy of the prosthesis base on the mucosa (superimposition of scans with / without prosthesis and of prosthesis alone) - The expression of molecular biomarkes (Saliva and peri-implant crevicular fluid (PICF) collection)	—

Measure

Time frame

The secondary endpoints are measured at each visit (1y, 3y, 5y after providing the patient with the prosthesis). - Implant and prosthetic survival - Biological parameters (marginal bone level, bleeding on probing, plaque index, probing depth, width keratinized mucosa, biological complications) at implant site - Technical parameters (wear of the restoration / antagonist) - Maintenance costs - Subjective evaluation of food impaction and plaque accumulation under the prosthesis (Before and after staining with methylene blue) - PROMS: patient satisfaction; ease of oral hygiene (general/specifc implant related); brushing discomfort - Aesthetics: Overall esthetic appearance (OES) - Soft tissue support (Facial analysis with facescans; mm) - Vestibular depth at implant site - Fit accuracy of the prosthesis base on the mucosa (superimposition of scans with / without prosthesis and of prosthesis alone) - The expression of molecular biomarkes (Saliva and peri-implant crevicular fluid (PICF) collection)

—

Countries

Switzerland

Contacts

Public ContactRiccardo Kraus

Klink für Rekonstruktive Zahnmedizin

riccardo.kraus@zzm.uzh.ch+41 44 634 04 04

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026