Hemodynamic response to peripheral and inspiratory muscle training in patients with cardiovascular disease: a randomized crossover study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00035668

Enrollment

Registered

2024-12-06

Start date

2025-05-15

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I20-I25

Interventions

Group 1: Single session of low-intensity protocols of three exercise modalities: - inspiratory muscle training (IMTLow - 40 percent intensity

3 sets of 15 repetitions), - isometric wall squat (IWSLow - 135 degrees intensity

2 bouts of 60 seconds), - dynamic leg press (DLPLow - 40 percent intensity

3 sets of 15 repetitions) and - isometric handgrip (IHGLow - 30 percent intensity

2 bouts of 60 seconds). Group 2: Single session of moderate to high-intensity protocols of three exercise modalities: - inspiratory muscle training (IMTHigh - 80 percent intensity

3 sets of 8 repetitions), - isometric wall squat (IWSMed - 115 degrees intensity

2 bouts of 60 seconds), - dynamic leg press (DLPHigh - 80 percent intensity

3 sets of 8 repetitions) and - isometric handgrip (IHGMed - 60 percent intensity

2 bouts of 40 seconds).

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Stable coronary artery disease

Exclusion criteria

Exclusion criteria: - No signed informed consent - Acute infection - Clinical instability in the last month (e.g. decompensated heart failure) - Functional class IV of New York Heart Association - Cardiac interventions less than 6 months before inclusion in this study - Hypertension grade 2 (= 160/100 mmHg at rest) - Untreated life-threatening cardiac arrhythmias at rest/or during exercise - Acute aortic dissection - Acute myocarditis/ pericarditis - Severe hypertrophic obstructive cardiomyopathy - Abdominal or inguinal hernia - Other clinical or/and functional limitations for the execution of evaluation tests and resistance training

Design outcomes

Primary

Measure	Time frame
Systolic blood pressure, diastolic blood pressure, cardiac output and heart rate	—

Secondary

Measure	Time frame
Oxygen saturation and perception of effort and tissue oxygenation	—

Countries

Germany

Contacts

Public ContactFlavia Mazzoli da Rocha

Deutsche Sporthochschule Köln

f.mazzolidarocha@dshs-koeln.de49 0221 4982 5076

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026