Prevention of intraabdominal abscesses requiring intervention after laparotomy for acute peritonitis through intraoperative peritoneal lavage with sodium hypochlorite/hypochlorous acid (NaOCl/HOCl) - a pilot RCT

Prevention of intraabdominal abscesses requiring intervention after laparotomy for acute peritonitis through intraoperative peritoneal lavage with sodium hypochlorite/hypochlorous acid (NaOCl/HOCl) - a pilot RCT - PREVENAT

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

DRKS

Registry ID

DRKS00035634

Enrollment

Registered

2024-12-23

Start date

2024-11-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K65

Interventions

Group 1: Standard of Care + additional instillation of 1000ml NaOCl/HOCl solution Group 2: Standard of Care

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with a peritonitis, capable of consenting, over 18 years

Exclusion criteria

Exclusion criteria: under 18 years, pregnant women, patients allergic to NaOCl/HOCl, planned second look, patients uncapable of consenting

Design outcomes

Primary

Measure	Time frame
Incidence of intraabdominal abscess formation requiring intervention	—

Secondary

Measure	Time frame
Postoperative morbidity and mortality, length of stay, time to bowel movement	—

Countries

Germany

Contacts

Public ContactSchaima Abdelhadi

Universitätsmedizin Mannheim

schaima.abdelhadi@umm.de+496213832225

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 9, 2026