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Cerebral perfusion measurement using transcranial ultrasound. A comparative study between contrast-enhanced ultrasound (CEUS) and CT perfusion (CT-P): a prospective, monocentric, exploratory clinical study.

Cerebral perfusion measurement using transcranial ultrasound. A comparative study between contrast-enhanced ultrasound (CEUS) and CT perfusion (CT-P): a prospective, monocentric, exploratory clinical study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00035601
Enrollment
20
Registered
2025-04-03
Start date
2025-02-28
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I60 I64

Interventions

Group 1: The patients receive intravenous US contrast medium for one sinlge examination. An ultrasound examination of the brain is then performed to determine the time-concentration curve. This serves

Sponsors

Universitätsmedizin Johannes-Gutenberg-Universität Mainz
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Previous acute ischemic cerebral infarction or previous cerebral perfusion disorder after subarachnoid hemorrhage with clinical indication for a CTP examination - Consent given by the patient themselves, their legal representative or an independent consultant physician

Exclusion criteria

Exclusion criteria: - Not of legal age - Known hypersensitivity to sulphur hexafluoride - Known right-to-left shunt - Severe pulmonary hypertension (pulmonary arterial pressure >90 mm Hg) - Other known severe cardiac pre-existing conditions (heart failure > NYHA I, endocarditis, CHD, arrhythmias, heart valve defects) - Uncontrolled systemic hypertension - Adult respiratory distress syndrome (ARDS) - Women of childbearing age, unless pregnancy has been ruled out - No consent available

Design outcomes

Primary

MeasureTime frame
The aim of the study is to compare the measurement of cerebral blood flow using contrast-enhanced ultrasound vs. conventional CT perfusion measurement

Countries

Germany

Contacts

Public ContactThomas Kerz

Universitätsmedizin Johannes-Gutenberg-Universtität Mainz

kerz@uni-mainz.de+496131172006

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 29, 2026