K05
Conditions
Interventions
Group 1: Patients who use the studied mouthwash solution (zinc lactate containing Meridol®, Colgate-Palmolive sarl Europe) twice daily after regular tooth brushing (15 ml of mouthwash solution for 30
Sponsors
Universitätsklinikum Hamburg-Eppendorf
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: a. Gingivitis, defined as at least 10% of sites with bleeding on probing. b. Intraoral detection of at least one of the 3 red complex bacteria. c. available for the duration of the study. d. Initial gingival index of > 1.5.
Exclusion criteria
Exclusion criteria: a. systemic diseases (e.g. diabetes mellitus). b. taking medication that can potentially or actually affect the intraoral microflora (e.g. immunosuppressants). c. taking/using systemic and/or local antibiotics in the last 3 months before starting the study. d. using an antimicrobial mouthwash in the last 3 months before starting the study. e. younger than 18 years. f. not able to give consent. g. pregnancy or breastfeeding. h. existing oral mucosal diseases. i. insufficient knowledge of German. j. untreated caries lesions. k. participating in another oral clinical study for the duration of this study. l. presence of orthodontic bands. m. dental prophylaxis performed in the last two weeks before the baseline examinations. n. smokers and/or users of tobacco products.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoral detection of Porphyromonas gingivalis, Tannerella forsythia and Treponema denticola 2 days, 14 days, 8 weeks and 12 weeks after baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| Pocket probing depths, bleeding on probing, gingival index and plaque index according to O'Leary 2 days, 14 days, 8 weeks and 12 weeks after baseline | — |
Countries
Germany
Contacts
Public ContactThomas Beikler
Universitätsklinikum Hamburg-Eppendorf
Outcome results
None listed