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SPLASH: SPlit thickness donor site Lipoaspirate AssiSted Healing

SPLASH: SPlit thickness donor site Lipoaspirate AssiSted Healing - SPLASH

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00035564
Enrollment
15
Registered
2024-11-22
Start date
2025-04-14
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

wound healing

Interventions

Group 1: In patients with an indication for reconstruction using split-thickness skin grafts, a wound inevitably forms at the donor site of the graft. This iatrogenic wound resembles an abrasion but e

Sponsors

Abteilung für Plastische, Hand- und Wiederherstellungschirurgie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Need for a split-thickness skin transplant, over 18 years of age, not pregnant years, not pregnant, BMI over 20 kg/m², regardless of gender.

Exclusion criteria

Exclusion criteria: Liver synthesis disorder (MELD >14), renal dysfunction (GFR <45 ml/min), previous surgical wounds in the area of the collection sites on the thigh, intake of anticoagulants.

Design outcomes

Primary

MeasureTime frame
Primary endpoints are complete re-epithelialization and its progression over time.

Secondary

MeasureTime frame
Secondary endpoints include the absolute and relative wound size reduction, as well as histopathological and immunological differences.

Countries

Germany

Contacts

Public ContactSilvan Maximilian Klein

Abteilung für Plastische, Hand- und Wiederherstellungschirurgie

silvan.klein@ukr.de0941 944-6763

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026