Effect of arginine bicarbonate on plaque pH during exercise in a randomized clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00035548

Enrollment

Registered

2024-11-21

Start date

2023-08-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Risk of demineralization of the enamel during sports

Interventions

Group 1: Description: Administration of arginine-hydrogen carbonate-sucrose solution during exercise (50% of individual VO2max). Duration and frequency: The intervention lasts 60 minutes and is carrie

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Healthy, physically active subjects Willingness to comply with the study requirements, including nutritional and oral hygiene requirements Willingness to carry out the physical exertion and measurements

Exclusion criteria

Exclusion criteria: Allergies and intolerances to the additive arginine hydrogen carbonate or serious general illnesses

Design outcomes

Primary

Measure	Time frame
What: Change in plaque pH by intake of arginine hydrogen carbonate. When: Measurements are taken before the start, during and after the end of exercise. How: pH measurements of the plaque.	—

Countries

Germany

Contacts

Public ContactMatthias Folwaczny

Ludwig-Maximilians-Universität München, Poliklinik für Zahnerhaltung und Parodontologie

Matthias.Folwaczny@med.uni-muenchen.de+49 89 440059333

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026