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Effects of trimodal prehabilitation on well-being and complications after transcervical pharyngeal/laryngeal cancer resections.

Effects of trimodal prehabilitation on well-being and complications after transcervical pharyngeal/laryngeal cancer resections. - PreHab study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00035537
Enrollment
50
Registered
2025-02-10
Start date
2025-02-05
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

advanced pharyngeal/laryngeal carcinomas

Interventions

Group 1: Prospectively selected patients with advanced pharyngeal/laryngeal carcinoma and indication for transcervical resection of this carcinoma according to the tumor board decision. Group 2: Retro

Sponsors

KRH Klinikum Nordstadt, HNO-Klinik
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Patients with histologically confirmed, advanced pharyngeal/laryngeal carcinoma. - According to the tumor board decision, transcervical surgical resection via laryngectomy or pharyngotomy with flap plasty is indicated.

Exclusion criteria

Exclusion criteria: - Age < 18 years - Patients who are unable to give consent - Women of childbearing age - Patients with derailed / difficult to control diabetes mellitus (“carbohydrate loading” not possible) - Patients with severe, uncontrolled COPD (breathing training not possible) - Patients with intolerances to Fortimel®, preOP® or their ingredients

Design outcomes

Primary

MeasureTime frame
The aim of this study is to test whether trimodal prehabilitation is possible for patients with advanced pharyngeal/laryngeal carcinomas in an outpatient setting before extensive tumor surgery. In addition, the aim is to evaluate the extent to which prehabilitation can improve the perioperative well-being of patients and reduce the postoperative complication rate.

Secondary

MeasureTime frame
- Improving the interdisciplinary preoperative care of patients with extensive pharyngeal/laryngeal carcinomas - Improvement in the quality of life of patients - Reduction of preoperative/perioperative anxiety and pain - Improvement of the sense of self-efficacy through active participation

Countries

Germany

Contacts

Public ContactAnja Pähler vor der Holte

KRH Klinikum Nordstadt, HNO-Klinik

anja.paehlervorderholte@krh.de00495119704377

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026