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Artificial intelligence (AI)-assisted histological diagnostics for cutaneous lymphomas

Artificial intelligence (AI)-assisted histological diagnostics for cutaneous lymphomas - KI-CL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00035531
Enrollment
300
Registered
2024-12-30
Start date
2024-09-02
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cutaneous lymphomas C84.0 C84.1

Interventions

Group 1: Patients with a clinically and pathologically validated diagnosis of cutaneous lymphoma with available archived or already digitized slides of skin samples taken as part of routine diagnostic

Sponsors

Charité-Universitätsmedizin Berlin
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with a clinically and pathologically validated diagnosis of cutaneous lymphoma with available archived or already digitized slides of skin samples taken as part of routine diagnostics. Control samples: Tissue samples from unaffected skin, e.g. from the margins of larger surgical specimens in the context of tumor re-excisions or similar. Specimens from patients with certain inflammatory dermatoses: psoriasis, atopic eczema, lichen planus, lichen sclerosus. Patients with early cutaneous lymphomas, pseudolymphomas and borderline findings.

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

MeasureTime frame
1) Case level: Accuracy, sensitivity, specificity and AUROC score + intersection over union for segmentation (mean and Std across cases)

Secondary

MeasureTime frame
2) Slide level (has the clinical picture for the slide been correctly assigned): Same endpoints as case level but for individual slides 3) Tile level (was the clinical picture correctly assigned to the image tiles): Same endpoints as slide level but for individual image tiles of a slide

Countries

Germany

Contacts

Public ContactRose K.C. Moritz

Klinik für Dermatologie, Venerologie und Allergologie, Charité-Universitätsmedizin Berlin

rose.moritz@charite.de+49 450 518065

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026