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Qualities of Dyspnea and their pathophysiological pattern regarding COPD patients

Qualities of Dyspnea and their pathophysiological pattern regarding COPD patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00035520
Enrollment
60
Registered
2025-01-09
Start date
2023-10-23
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J44

Interventions

Group 1: In a period from 10/23 to probably 01/25, patients who are treated either as inpatients or outpatients at the Cologne-Merheim Lung Clinic (KdSK) and suffer from COPD GOLD II-IV will be examin

Sponsors

Krankenhaus Köln-Merheim
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Previously known or newly diagnosed COPD according to the definition of obstruction according to the bronchospasmolysis test Z value < -1.64 - Smoker/ex-smoker with at least 20 pack-years - Consent to data protection and patient information - Willingness to answer the questionnaires in full - Linguistic and cognitive abilities to answer the questionnaires

Exclusion criteria

Exclusion criteria: - Patient age 300/microliter - Alpha-1-antitrypsin deficiency - FENO values > 40 ppm - Pre-existing conditions (asthma, bronchiectasis, ILD, bronchial CA, other pneumological diseases)

Design outcomes

Primary

MeasureTime frame
Validation/falsification of the hypothesis: Dyspnea is heterogeneous What causes dyspnoea in COPD? - Classify dyspnoea as a general symptom

Secondary

MeasureTime frame
Validation/falsification of the hypotheses: 1. identification of the predictors for the individual dyspnea qualities based on the diagnostics performed 2. differences in the severity of dyspnoea between the identified COPD types 3. differences in the frequency of exacerbations between the COPD types characterized by different dyspnoea qualities 4. do hyperinflated patients have impaired diaphragmatic function?

Countries

Germany

Contacts

Public ContactMaximilian Zimmermann

Krankenhaus Köln-Merheim

ZimmermannMa@kliniken-koeln.de+49221890713468

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026