lung-protective ventilation
Conditions
Interventions
Group 1: Cotroll-group: Pressure controlled ventilation with a short inspiratory ramp time
Group 2: Study-group: Pressure controlled ventilation with a long inspiratory ramp time
Sponsors
Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinik Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adult patients, scheduled for elective brain surgery in supine position with planned time of surgery for at least four hours were included.
Exclusion criteria
Exclusion criteria: age under 18 years, unable to give consent, terminal pulmonary disease, pregnancy, body mass index (BMI) greater than 35 kg/m², American Society of Anaesthesiologists (ASA) physical status greater than three, history of taking immunosuppressants, implanted electronic devices as pacemakers, implantable cardioverter-defibrillators (ICD), or cardiac resynchronization therapy defibrillators (CRT-D), severe anemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the mechanical power between study and controll group | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of the Horovitz index between study and control group during the intervention Comparison of the change of compliance during the time of mechanical ventilation between study and controll group Comparison of the area of ventilation between study and control group during the intervention Change of lungs specific biomarkers in dependance of ventilation time and group assignment Evaluation of postoperative pulmonary complications in dependance of group assignment | — |
Countries
Germany
Contacts
Public ContactJohannes Hell
Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinik Freiburg
Outcome results
None listed