Quadriceps Elastography and STrength: an evaluation of the quantity and properties of the quadriceps muscle

Quadriceps Elastography and STrength: an evaluation of the quantity and properties of the quadriceps muscle - QUEST

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00035467

Enrollment

200

Registered

2025-02-03

Start date

2025-04-01

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

a) 50 healthy volunteers b) 50 out-patients visiting the ambulance of the department of gastroenterology c) 50 in-patients in the standard ward of the department of gastroenterology d) ~25 critically ill patients in a medical ICU (predominantly gastrointestinal) e) ~25 critically ill patients in a surgical ICU (predominantly cardiac surgery)

Interventions

Group 1: Adult patients after informed consent and fitting in one of the predefined subgroups: a) 50 healthy volunteers b) 50 out-patients visiting the ambulance of the department of gastroenterology

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult patients after informed consent and fitting in one of the predefined subgroups: a) 50 healthy volunteers b) 50 out-patients visiting the ambulance of the department of gastroenterology c) 50 in-patients in the standard ward of the department of gastroenterology d) ~25 critically ill patients in a medical ICU (predominantly gastrointestinal) e) ~25 critically ill patients in a surgical ICU (predominantly cardiac surgery)

Exclusion criteria

Exclusion criteria: 1. Patients < 18 years, pregnant or lactating patients 2. Patients unable to consent or follow instructions from medical team (cognitive, psychiatric, or severe language barriers)

Design outcomes

Primary

Measure	Time frame
Correlation of quadriceps elasticity with quadriceps muscle mass quadriceps layer thickness (QMLT) measured via sonography	—

Secondary

Measure	Time frame
Correlation of quadriceps elasticity with other parameters associated with the quadriceps muscle: -1-Minute Sit to stand test -Bioimpedance Analysis -Nutritional status measured by GLIM Criteria -Muscle status measured by EWGSOP 2 Criteria -Frailty measured by Clinical Frailty Scale (CFS) -Sarcopenia measured by the SARC-F Questionnaire -Handgrip strength (HGS) -Mid-upper arm circumference (MUAC) - Cross sectional imaging (CT or MRI if performed for clinical routine)	—

Measure

Time frame

Correlation of quadriceps elasticity with other parameters associated with the quadriceps muscle: -1-Minute Sit to stand test -Bioimpedance Analysis -Nutritional status measured by GLIM Criteria -Muscle status measured by EWGSOP 2 Criteria -Frailty measured by Clinical Frailty Scale (CFS) -Sarcopenia measured by the SARC-F Questionnaire -Handgrip strength (HGS) -Mid-upper arm circumference (MUAC) - Cross sectional imaging (CT or MRI if performed for clinical routine)

—

Countries

Germany

Contacts

Public ContactAileen Hill

Uniklinik RWTH Aachen

ahill@ukaachen.de+4917644432574

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026