Longitudinal study on the assessment of neuropsychological performance domains in trans people as a function of gender reassignment hormone treatment

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00035445

Enrollment

Registered

2024-11-22

Start date

2024-10-07

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F64.0

Interventions

Group 1: Psychiatrically unremarkable people with transsexualism (F64.0 according to ICD-10) without previously initiated gender reassignment hormone treatment In this arm, the participants are exami

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: - Ability to give consent and existing signed consent form - Right handed

Exclusion criteria

Exclusion criteria: - Missing ability to give consent or missing signed consent form - Psychological disorders (current severe depressive episode, clinical relevant anxiety symptomatic, dependency disorders, Post-traumatic-stress-disorder, Austism-spectrum disorder, identity disorders) - Intelligence deficits/reduction - neurological disorders - pregnancy

Design outcomes

Primary

Measure	Time frame
- California Verbal Learning test - Mental Rotation test - Multifaceted Empathy test - Go/NoGo task - Serial Reaction Time task - Mnemonic Similarity task - Point Substraction Aggression paradigm	—

Secondary

Measure	Time frame
PHQ-9, SAS, AQ-K, PCL-5, WHOQUOL-BREF,German Aggression Questionnaire, Emotion Regulation Questionnaire	—

Countries

Germany

Contacts

Public ContactInken Tödt

Zentrum für Integrative Psychiatrie - Institut für Sexualmedizin und Forensische Psychiatrie und Psychotherapie

Inken.Toedt@uksh.de+49 431 500 98263

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026