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Validation of prehospital VA ECMO in OHCA via implementation in the regular EMS

Validation of prehospital VA ECMO in OHCA via implementation in the regular EMS

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00035400
Enrollment
500
Registered
2024-12-03
Start date
2013-01-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I46.9

Interventions

Group 1: Retrospective study of patients who have been treated with VA ECMO (ECPR) at the site since 2013 for prehospital cardiac arrest (OHCA).

Sponsors

Universitätsklinikum Regensburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 65 years Observed out-of-hospital cardiac arrest Initiation of conventional CPR measures by bystanders or medical personnel within a maximum of 10 minutes after the event No ROSC (Return of Spontaneous Circulation) after 5-10 minutes of ACLS (Advanced Cardiovascular Life Support) according to the currently valid ERC (European Resuscitation Council) Guidelines Persistent hemodynamic instability despite intermittent ROSC

Exclusion criteria

Exclusion criteria: Treatment refusal by the patient (e.g., existing advance directive) Age 65 years CPR duration > 60 minutes until the arrival of the ECLS team Cardiac arrest due to a non-cardiac cause (e.g., trauma, dissection, bleeding) Initiation of thrombolysis therapy before the arrival of the ECLS team Known severe systemic diseases such as liver cirrhosis Child C, heart failure NYHA IV, or COPD Gold IV Malignant (and incurable) underlying disease Presence of vascular prostheses in the inguinal vessels or abdominal aorta Rejection of the procedure by the attending emergency physician Rejection of the procedure by the patient's attending family members

Design outcomes

Primary

MeasureTime frame
Survival to hospital discharge rate

Secondary

MeasureTime frame
Survival to hospital discharge with good neurological outcome. Longtime survival: 1 year/5 years

Countries

Germany

Contacts

Public ContactDirk Lunz

Universitätsklinikum Regensburg

dirk.lunz@ukr.de+4994194417986

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 21, 2026