Proteom analysis, STBAD, Aortic dissection (any part) I71.0
Conditions
Interventions
Group 1: Patients with Stanford type B aortic dissection (STBAD) are routinely provided with intensive medical care, unless there is an emergency indication for a TEVAR.
In addition, blood samples are
Sponsors
Universitätsklinikum Heidelberg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Written consent to participate in the study (HeiPoDD study information + information on proeteome analyses for the prediction of complications in thoracic aortic dissections) - Age > 18 years - Radiologically confirmed evidence of a thoracic aortic dissection Stanford type B - Capacity to consent - The control patients from the HeiPoDD study consented to inclusion in the HeiPoDD study
Exclusion criteria
Exclusion criteria: - Age < 18 years - Cancellation/refusal of the radiological examination - Lack of written consent from the patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The progression of an acute aortic dissection, as measured by follow-up CT-A examinations with the need for surgical treatment, can be recognized by the proteome expression profile over the course of monitoring. | — |
Secondary
| Measure | Time frame |
|---|---|
| The proteome expression profile correlates with radiological findings over time after acute aortic dissection (false channel thrombosis, expansion of the aortic diameter, etc.). In addition, the proteome expression profile correlates with clinical parameters of the monitoring phase of an acute aortic dissection (therapy-refractory hypertension, pain, etc.). | — |
Countries
Germany
Contacts
Public ContactPhilipp Erhart
Universitätsklinikum Heidelberg
Outcome results
None listed