Microbiome Assessment In Infants At Risk For Hypoxic Ischemic Encephalopathy

Microbiome Assessment In Infants At Risk For Hypoxic Ischemic Encephalopathy - MARIE

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00035360

Enrollment

Registered

2024-10-25

Start date

2022-01-01

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

P91.6

Interventions

Group 1: Multicenter, prospective observational study of newborns with perinatal asphyxia under standardized intensive care (clinical data collection) and neurological diagnostics (EEG/aEEG, GMA) incl

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: severe postnatal adjustment disorder of a newborn (asphyxia) with HIE and hypothermia treatment

Exclusion criteria

Exclusion criteria: - Preterms <35+0 gestational weeks - Severe congenital malformations

Design outcomes

Primary

Measure	Time frame
Degree of HIE and prediction of cerebral palsy (GMA, MRI)	—

Secondary

Measure	Time frame
Neurological long-term outcome at the age of 2 years (Bayley scales) and 5 years (Gross Motor Function Test, Wechsler Test WPPSI-III, Strength and Difficulties Questionnaire)	—

Countries

Germany

Contacts

Public ContactTatyana Koch

Universitätskinderklinik Würzburg

koch_t1@ukw.de+4993120145851

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026