R64
Conditions
Interventions
Group 1: Control group: Living kidney donors - intraabdominal and subcutaneous adipose tissue was collected intraoperatively
Group 2: Pancreatic cancer patients without cachexia (defined by body weigh
Sponsors
Universitätsklinkum Heidelberg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Suspected pancreatic cancer (for pancreatic cancer groups) - healthy kidney donors (control group) - Written informed consent
Exclusion criteria
Exclusion criteria: - Chronic inflammatory diseases - History of cancer diagnosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Since this is a non-interventional observational study with tissue collection for exploratory purposes, neither primary nor secondary endpoints are defined. The main objective of the study is to characterize local changes in intra-abdominal and subcutaneous adipose tissue in the context of pancreatic cancer-associated cachexia at the single-cell level. A secondary objective is to correlate the obtained results with postoperative weight progression, survival rate, quality of life, and the occurrence of tumor recurrence. | — |
Secondary
| Measure | Time frame |
|---|---|
| Since this is a non-interventional observational study with tissue collection for exploratory purposes, neither primary nor secondary endpoints are defined. The main objective of the study is to characterize local changes in intra-abdominal and subcutaneous adipose tissue in the context of pancreatic cancer-associated cachexia at the single-cell level. A secondary objective is to correlate the obtained results with postoperative weight progression, survival rate, quality of life, and the occurrence of tumor recurrence. | — |
Countries
Germany
Contacts
Public ContactMax Heckler
Universitätsklinkum Heidelberg
Outcome results
None listed