F40-F48
Conditions
Interventions
Group 1: To research the biological basis of dissociative or functional disorders and to detect molecular genetic biomarkers, extensive molecular genetic analyzes should be carried out at the level of
Sponsors
Universitätsklinikum Bonn, Klinik und Poliklinik für Psychiatrie und Psychotherapie
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Arm 1: (Patients with dissociative and functional disorders): Adult patients up to and including 65 years of age with diagnoses in the area of ??affective disorders (ICD-10 F30-F39), neurotic, stress and somatoform disorders (ICD-10 F40-F48), behavioral problems with physical disorders and factors (F50-F59), personality and behavioral disorders (ICD-10 F60-F69) and/or behavioral and emotional disorders with onset in childhood and adolescence (ICD-10 F90-F98). Arm 2 (patients with neurological diseases): Adult patients up to and including 65 years of age with diagnoses in the areas of inflammatory diseases of the central nervous system (ICD-10 G00-G09), extrapyramidal diseases and movement disorders (ICD-10 G20-G26), episodic and paroxysmal diseases of the central nervous system (ICD-10 G40-G47) and/or with symptoms affecting the nervous system and the Affect the musculoskeletal system (ICD-10 R25-R29). Arm 3: (Patients with syncopal seizures): Adult patients up to and including 65 years with the diagnosis of syncope and collapse (ICD-10 R55) and/or other and unspecified convulsions (ICD-10 R56.8). Arm 4: No further inclusion criteria
Exclusion criteria
Exclusion criteria: All study arms: Younger than 18 or older than 65 years, lack of capacity to consent, acute suicidality, brain surgery that took place. Certain infectious and parasitic diseases (ICD-10 A00-B99), malignant tumor diseases (ICD-10 C00-C97), organic mental disorders (ICD-10 F00-F09), serious mental and behavioral disorders caused by psychotropic substances (from ICD-10 F10-F19), schizophrenia, schizotypy and delusional disorders (ICD-10 F20-F29), Intellectual disorders (ICD-10 F70-F79), developmental disorders (ICD-10 F80-F89), system atrophies that predominantly affect the central nervous system (ICD-10 G10-G14), other degenerative diseases of the nervous system (ICD-10 G30-G32), cerebrovascular diseases (ICD-10 I60-I69), pregnancy, birth and postpartum period (ICD-10 ICD-10 O00-O99).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Genome-wide genotyping and whole genome sequencing | — |
Secondary
| Measure | Time frame |
|---|---|
| DNA modification (epigenetics) | — |
Countries
Germany
Contacts
Public ContactMax Christian Pensel
Universitätsklinikum Bonn, Klinik und Poliklinik für Psychiatrie und Psychotherapie
Outcome results
None listed