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Molecular biological and cellular characterization of urological tumours tumors for the investigation of tumorigenesis, metastasis and therapy response response to therapy, as well as establishment of an organoid and biobank of urological tumors

Molecular biological and cellular characterization of urological tumours tumors for the investigation of tumorigenesis, metastasis and therapy response response to therapy, as well as establishment of an organoid and biobank of urological tumors

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00035211
Enrollment
300
Registered
2024-10-07
Start date
2024-10-21
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tumors in urological patients C64 C61 C67 C65 C66 C60 C62 C63

Interventions

Group 1: Patients with urological tumors Patients suspected of having a urological carcinoma (prostate, renal cell, testicular, ureteral, renal pelvis, or bladder cancer) undergo surgical treatment.

Sponsors

Universitätsklinikum Ulm
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult patients (=18 years of age) who are capable of being informed and who have a urological tumor or the suspicion of the presence of a tumor disease, available written declaration of consent

Exclusion criteria

Exclusion criteria: Lack of consent from the patient

Design outcomes

Primary

MeasureTime frame
The overarching goal is to establish a biobank of tissue (confirmatory tumor and metastases, control tissue), blood, urine, stool as well as organoids, immune cells and stroma cells stromal cells (in the sense of a living biobank) from patients with urological tumors and tumors as well as control patients who have an underlying urological disease and are therefore undergoing disease and are therefore undergoing surgery, but do not have a tumor disease. have tumor disease. On the other hand, tissue from tumor patients that has nothing to do with the with the tumor disease are used as a control (e.g. renal pelvis tissue in renal cell carcinoma). renal pelvis tissue in renal cell carcinoma, see below).

Secondary

MeasureTime frame
In addition, further therapy-relevant data (see below) will be collected prospectively. For this purpose different data parameters are obtained in addition to the biomaterials. The biobank serves as the basis for various other translational approaches to improve the improve the diagnosis and treatment of urological tumor entities in the future.

Countries

Germany

Contacts

Public ContactFelix Wezel

Universitätsklinikum Ulm

felix.wezel@uniklinik-ulm.de+4973150058000

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026