Occupational disease no. 5103 "Squamous cell carcinoma or multiple actinic keratoses caused by natural UV radiation"
Conditions
Interventions
Group 1: Intervention group:
Provision of different topical sunscreens and a health educational measure (sunscreens for the entire study period + health educational measure 10 minutes at the beginnin
Sponsors
Universität Osnabrück
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Intensively exposed to solar UV radiation of regularly one hour or more per day, as defined in the occupational health rule no. 13.3 from the Federal Institute of Occupational Safety and Health (AMR 13.3).
Exclusion criteria
Exclusion criteria: Outdoor workers with a known or rather self-reported allergy to any of the ingredients of the study products. Skin diseases that could influence the study results (e.g., psoriasis vulgaris).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increasing the frequency of the occupational as well as the personal and private use of topical sunscreens using a questionnaire modified according to Symanzik et al. for sun protection behaviour at baseline, after 3 months and after 6 months. In addition, internal UV-dose and immune response will be used determined by the levels of cis-urocanic acid (cUCA), interleukin-1 alpha (= IL-1a) and interleukin-1 receptor antagonist (= IL-1 RA) from collected Stratum corneum samples at the beginning of the study and after 3 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Increase in sun protection behaviour, especially with regards to the use of topical sunscreens using a questionnaire modified according to Symanzik et al. for sun protection behaviour and the OccuSun Safe questionnaire extended by questions on the private and personal sun protection behaviour at baseline, after 3 months and after 6 months. In addition, internal UV-dose and immune response will be used determined by the levels of cis-urocanic acid (cUCA), interleukin-1 alpha (= IL-1a) and interleukin-1 receptor antagonist (= IL-1 RA) from collected Stratum corneum (= SC) samples at the beginning of the study and after 3 months. Increase in knowledge about sun protection and skin cancer using the Skin Cancer and Sun Knowledge (SCSK) scale at baseline, after 3 months and after 6 months. Evaluation of the user acceptance of the provided sunscreens using a user acceptance questionnaire according to Symanzik et al. which was adapted to sunscreen use at the end of the study (after 6 months). Biomarkers of internal UV-dose and immune response in SC samples. | — |
Countries
Germany
Contacts
Public ContactSwen Malte John
Universität Osnabrück
Outcome results
None listed