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T2* mapping of the knee joint cartilage under mechanical load during alpine skiing: establishment and longitudinal assessment

T2* mapping of the knee joint cartilage under mechanical load during alpine skiing: establishment and longitudinal assessment

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00035129
Enrollment
30
Registered
2024-10-11
Start date
2024-05-13
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Group 1: The study population is made up of experienced alpine skiers of different age groups. 6 people participated in the feasibility study and there will be around 20 participants in the longitudi

Sponsors

Universitätsklinikum Ulm, Klinik für diagnostische und interventionelle Radiologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: -experienced alpine skiers -written informed consent of the participants after enlightenment

Exclusion criteria

Exclusion criteria: -age <18 years -complete or partial incapacitation -previous operations on the knee joints, e.g. cruciate ligament reconstruction or partial meniscus resection -pre-existing osteoarthritis/chondromalacia, focal osteochondral lesions of the knee joints -malalignment of the leg axes or individual handicaps that prevent symmetrical bilateral leg loading -implants, especially in the lower extremities (e.g. knee prosthesis, plate osteosynthesis, etc.) -general (relative) contraindications to an MRI examination: +pacemaker, defibrillator +insulin pump, ferromagnetic intracranial clips +metal splitter in the eye or other life-threatening localizations +Cochlea-implants, pregnancy, permanent make-up -unstable medical condition that interferes with the examination -claustrophobia

Design outcomes

Primary

MeasureTime frame
Changes of the T2*-values of the knee cartilage between baseline before skiing and measurements directly after and the morning after mechanical loading in alpine skiing. This is a retrospective data analysis of MRI-generated images.

Secondary

MeasureTime frame
Differences in the T2*-values before and after the ski season

Countries

Germany, Switzerland

Contacts

Public ContactMeinrad Beer

Universitätsklinikum Ulm. Klinik für diagnostische und interventionelle Radiologie

meinrad.beer@uniklinik-ulm.de+4973150061001

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026