F44.4 R49.1
Conditions
Interventions
Group 1: This study arm is part of the prospective, randomised, controlled comparative therapy study. In arm 1, patients receive the intensive phoniatric acute intervention (IPA) for dissociative voic
Sponsors
Universitätsklinikum Münster (UKM), Klinik für Phoniatrie und Pädaudiologie
Eligibility
Sex/Gender
All
Age
18 Years to 69 Years
Inclusion criteria
Inclusion criteria: All participants: - are between 18 and 69 years old - use German as their first or main language - have right-handedness Patients with dissociative voice disorders: - have a diagnosed dissociative voice disorder (psychogenic dysphonia/aphonia) - have already received speech therapy treatment of at least 10 therapy hours
Exclusion criteria
Exclusion criteria: All participants: - left-handedness, ambidexterity (using the Edinburgh handedness questionnaire (EHI)) - motor, cognitive, anatomical or sensory disorders that may be associated with speech and voice deficits - speech fluency disorder (stuttering, poluttering) - profound developmental disorder (e.g. autism) and severe congenital somatic diseases - pre-existing severe concomitant mental illness (schizophrenia, history of psychotic episode, severe depressive episode, post-traumatic stress disorder, bipolar disorder, personality disorder according to DSM-V, current or history of substance-related addiction) - severe cognitive disorder (delirium, dementia) - central nervous system medication taken within the last 3 months - acute influence of psychoactive substances (alcohol, cannabis, etc.) at the time of the study - MRI contraindications (e.g. metallic objects in/on the body, pregnancy, breastfeeding, claustrophobia) Patients with dissociative voice disorders: - existence of dysphonia / aphonia for more than 2 years - ongoing speech therapy - previous psychotherapy within the last 5 years or > 30 hours of psychotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Study arm 1 and 2: phoniatric variables according to the extended protocol of the European Laryngological Society Study arm 3: change in the voice quality and voice sound perceived by the patients | — |
Secondary
| Measure | Time frame |
|---|---|
| Study arm 1 and 2: - phoniatric variables: acoustic analysis, aerodynamic analysis, videolaryngostroboscopy, subjective voice quality - psychiatric variables: quality of life, general stress symptoms and disorders (e.g. dissociative disorders, somatization, post-traumatic stress disorder) - ROI in fMRI and MRS (MR-spectroscopy) Study arm 3: relapses, remaining need for treatment, subjective voice quality, influence on everyday life, perception of the therapy received and satisfaction with the intervention received | — |
Countries
Germany
Contacts
Public ContactPhilipp Mathmann
Universitätsklinikum Münster (UKM), Klinik für Phoniatrie und Pädaudiologie
Outcome results
None listed